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Tuesday, 25 October 2005 · Issue 181 | |||
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IN THIS WEEK'S BioEDGE Huge increase demands ethical response Embryos may be able to correct defects Many reviewers have links to manufacturers Hwang uses Korean expertise to supply the world Stanford to attempt curing rare brain disease TO OUR READERS: Kass farewells bioethics council with ageing report
In a column in the Washington Post, Kass summed up the message of the report: "Against our confidence in mastery and control, we need to remember that old age and dying are not problems to be solved but human experiences that must be faced. In the years ahead, we will be judged as a people by our willingness to stand by one another, not only in the rare event of natural disaster but also in the everyday care of those who gave us life and to whom we owe so much." ~ Washington Post, Sept 29; www.bioethics.gov
However, it now appears that defective embryos are able to correct defects as they mature. One American experiment discovered that about half of the cells in "defective" embryos were normal by the blastocyst stage. This suggested two things to the fertility specialists. First, that defective embryos might be a viable source of embryonic stem cells, and second, that many embryos discarded as defective could have developed into healthy babies. One initiative to emerge from the meeting is a US database to track the safety of PGD. American clinics are not presently required to report their data. ~ Nature, Oct 20
Financial links to drug use guidelines Although such links have been strongly criticised, the bodies which produce the guidelines counter that there simply aren't enough experts without potential conflicts of interest. The American Diabetes Association estimates that three-quarters of the members eligible to write clinical guidelines have conflicts of interest. ~ Nature, Oct 20
South Korea cloner opens stem cell "library" in US and UK One of the main attractions of Hwang's initiative is bypassing political, regulatory and financial barriers to embryonic stem cell research in the US. According to an article in the New England Journal of Medicine, a number of prominent US stem cell scientists are enthusiastic about the project because it will enable them to study diseases. Many researchers believe that human embryonic stem cells may turn out to be even more valuable for studying the mechanisms of disease and for screening experimental drugs than for cell-based therapy, although it is their potential for providing replacements for dead or diseased cells and tissues that has captured the public imagination," writes Dr Susan Okie, a contributing editor of the NEJM. An article in the on-line magazine Slate by David Plotz explains how South Korea has managed to become the cloning capital of the world without much funding or even a track record in biotech. The key to success is the extraordinary ability of Hwang himself, but some national characteristics help make his work more productive. Koreans are not "preoccupied with moral questions about the beginning of life". Despite an official ban on abortions, it has one of the highest abortion rates in the world. Korean are "extremely open to medical self-improvement" -- they may have the highest cosmetic surgery rates in the world. The enormous pressure on Korean couples to have their own genetic children has also generated a large IVF industry with extremely high skills. (Plotz speaks of the "Chopstick Theory of Scientific Supremacy" -- that Koreans are skilled at manipulating embryos because of their handiness with chopsticks.) And Koreans work harder. The scientists who work in Hwang's laboratory have boring, repetitive jobs, but work seven days a week without holidays. ~ New England Journal of Medicine, Oct 20; Slate, Oct 19
Foetal stem cells to be used to cure children The idea is to inject stem cells from aborted foetuses into the children's brains with the hope that they will graft to existing brain cells and replace the defective cells. It is a risky operation, but the alternative is certain death from the disease, say supporters of the experiment. A company called Stem Cells Inc, which was founded by Irving Weissman, a leading figure in California stem cell research, is conducting the study. It obtains its foetal tissue from a non-profit organisation. The ultimate goal of the experiment is to use the same technique on patients suffering from other brain disorders. ~ AP, Oct 21
IN BRIEF: DNR; patents; cosmetic surgery; animal liberation Patents: Nearly a fifth of all human genes have been patented, according to a study by academics at the Massachusetts Institute of Technology. In an article in Science, they says that the situation could "increase the costs of genetic diagnostics, slow the development of new medicines, stifle academic research and discourage investment in downstream research and development." ~ The Age (Melbourne), Oct 15 Cosmetic surgery: Britain is thinking of toughening guidelines on cosmetic surgery after a steep rise in the number of botched operations by "cowboy" doctors in the UK and overseas. Plastic surgery is booming in the UK and high fees are forcing patients to seek help overseas. "One of the reasons many operations are cheap is that they don't offer any aftercare if things go wrong," says the president-elect of the British Association of Plastic Surgeons, Dr Douglas McGeorge. ~ London Telegraph, Oct 19 Animal liberation: Two members of a radical US animal rights group have been charged with multiple counts of animal cruelty in North Carolina. The two belong to People for the Ethical Treatment of Animals. Local shelters thought that they were taking animals to place them in new homes. Instead they allegedly gave them lethal injections and dumped the bodies in supermarket bins. The president of PETA, Ingrid Newkirk, defended their actions. ~ London Telegraphy, Oct 18
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Australasian Bioethics Information ISSN 1446-2117 Website:www.australasianbioethics.org BioEdge editor: Michael Cook New Zealand Contributing Editor: Carolyn Moynihan The BioEdge privacy policy Your subscription information will be kept private and is not publicly accessible. Your email address and other information will never be sold to a third party or given out without your consent. You may cancel your subscription at any time. |