Four senior doctors have been arrested in Israel for experimenting illegally upon thousands of elderly patients without their consent over several years. According to Haaretz, they have been accused of "wrongful death through negligence, abuse of helpless victims, aggravated assault, fraud, violation of a statutory obligation and interference in an investigation." At least one patient died as a direct result of an experiment and another 12 died during or shortly after another one. At least four doctors at two hospitals became renowned geriatric experts after publishing articles based on the experiments.
The Health Ministry has released a report on the scandal which found that some of these experiments had no medical or scientific benefit. Some were conducted over the protests of other doctors. The report also blasted ethics committees at two hospitals, Kaplan Hospital in Rehovot and the Hartzfeld Geriatric Hospital in Gedera, for approving inappropriate experiments, and the hospitals' administration for failing to act on complaints. ~ Haaretz.com, Oct 10
The Blair government has appointed a controversial retired Anglican bishop as temporary head of its fertility authority. Lord Harries of Pentregarth, formerly Richard Harries, Bishop of Oxford, replaces Suzi Leather as chairman of the Human Fertilisation and Embryology Authority until it disappears in a merger with Human Tissue Authority next year.
Lord Harries has been in the line of fire before, as the man who sparked the debate about homosexual bishops by nominating a gay priest as an Anglican bishop several years ago. More relevant to his current responsibilities is the fact that he has no qualms about tinkering with embryos. "I don't feel troubled in my conscience about it because, as I say, I don't regard that very early embryo, which is just a small bundle of multiplying cells, as having the rights of a human being," he told the London Times in a wide-ranging interview. He also supports abortion, although he is troubled by abortion on demand.
Even within IVF circles Lord Harries views are liberal. He does not mind using IVF to help grandmothers have babies and he does not believe that the welfare of a child includes the need for a father. That should go," he said. "I don't think it's very useful because I think studies have shown that two people of the same sex together can be good parents."
In the interview, he also signalled that the HFEA will probably rule that only single embryos can be implanted in most IVF mothers to bring down the number of twin and triplet births. ~ London Times, Oct 14
A stem cell scientist from Massachusetts Institute of Technology visiting Australia last week made a vigorous attack upon the science and ethics of therapeutic cloning. Associate Professor James Sherley spoke with several MPs ahead of a vote in Canberra about legalising cloning. He minced no words: "adult stem cell research is a viable and vibrant path to new medical therapies. Even calling them an alternative to embryonic stem cells misinforms the public. Why? Because embryonic stem cells provide no path at all."
Although Sherley also regards human embryos as human beings, with a right not to be experimented upon, he supported his ethical concerns with scientific arguments. First, if cloned animals notoriously have serious birth defects, cloned embryos must also have them, making tissues derived from them dangerous and ineffective.
Second, cloned embryonic stem cells normally form tumours when transplanted into adult tissues. Third, the continuous renewal and repair of tissue is the work of adult stem cells. Embryonic stem cells might be able to replace adult tissues, but they will not replace the adult stem cells.
Even the proposal to use cloned human embryos to investigate adult disease mechanisms has no scientific legs. The worth of such studies will be limited by the inherent genetic defects in cloned embryos and, fundamentally, diseases that arise in the adult are not likely to manifest until later in embryonic development, if at all before birth," he wrote in the Australian newspaper.
As the vote on the issue approaches, parliamentarians are being intensely lobbied and lectured by both sides of the debate. The result is still too early to call. However, the premier of the state of Victoria, Steve Bracks, has already vowed to legislate for therapeutic cloning, even if research in his state would not be eligible for Federal funding. Victoria is home to half of Australia's biotech industry, and Bracks fears a brain drain unless scientists get what they want. ~ Australian, Oct 12
Women with diseases like diabetes and cystic fibrosis should be encouraged to donate their eggs for experiments in therapeutic cloning, according to an Australian scientist. Professor Bob Williamson, of the University of Melbourne, says "it is totally appropriate ethically to look to people who have a disease in their family as the first person to participate in research. Who is more logical to participate in research in type one diabetes than young women who have type one diabetes?" Professor Williamson said that collecting eggs for research could become a problem and that eggs from disease-bearing women might help bridge the gap. The lobby group Women's Forum Australia commented that egg collection posed serious risks to women's health. ~ news.com.au, Oct 11
In the wake of North Korea's claim to have exploded a nuclear bomb, articles featuring criticism of the cruel and secretive government have again flooded Western newspapers. The London Sunday Times reports that North Korea's obsession with racial purity has led to the killing of disabled infants and the forced abortion of women who bore children to Chinese men. Refugees paint a picture of a regime which is less a Communist workers' state than a monarchy based on notions of racial superiority.
A North Korean refugee doctor, Ri Kwang-chol, says that deformed babies are killed soon after birth. "There are no people with physical defects in North Korea," he told a seminar in Seoul.
Women who escape over the border into China are often sold by traffickers. If they are pregnant when they are caught and returned to North Korea, soldiers abort the foetus and the babies are suffocated or tossed into bins. The Korean Bar Association says that 58% of defectors interviewed by its lawyers have reported stories of forced abortions. A 2003 human rights report by the US Committee for Human Rights in North Korea found that the regime was practicing what it termed "ethnic infanticide". ~ London Sunday Times, Oct 15
The world's first cat cloning company, Genetic Savings & Clone, has shut its doors because of low demand. Since the company opened in 2000, it managed to clone five cats, but sold only two of them. Animal welfare activists were delighted at the news. "It's no surprise the demand for cloned pets is basically non-existent, and we're very pleased that Genetic Savings & Clone's attempt to run a cloning pet store was a spectacular flop," says Wayne Pacelle, head of the Humane Society of the United States. "It's not just a bad business venture, but also an operation grounded on the abuse of animals."
The company was started by billionaire and University of Phoenix founder John Sperling, who had hoped to clone his hunting dog Missy. It never happened. ~ AP, Oct 11
Most British sperm banks have reported shortages ever since the UK government made it possible for IVF children to find out who their biological parents are. Recruitment has become more difficult and costly, with many potential donors discouraged by the paperwork and by unfounded rumours that the new law might be retroactive. However, Manchester Fertility Services has actually increased the number of its donors. Its secret is a change of attitude by the clinics themselves. "We regard donors as special people who need to be cherished," it says. It tries to court potential donors with close attention to every step of the relationship.
With the new regulations a new type of donor appears to have emerged: an older married man with children of his own. "Gone are the days when sperm donation was regarded as 'beer money'," writes a team from MFS. ~ BioNews, Oct 16
Everyone expects political ads on television to oversimplify things, but American ads dealing with stem cell research make mere oversimplification look like a PhD dissertation. The suggestion that embryonic stem cell research might not deliver the goods is interpreted as despicable Pharisaism. This ad aimed at a Republican congressman from upstate New York doesn't even feature sick patients, only healthy patients who worry that they might get sick.
Or take this one from a Congressional race in Wisconsin designed to kneecap Republican John Gard.
The music is a bit odd, but the ad is quite effective. It cites favourable Republican favourites like Orrin Hatch and Nancy Reagan, juxtaposing them with Darth Vaders from "the extreme right" like disgraced Congressman Tom Delay, TV evangelist Pat Robertson and Focus on the Family president James Dobson. Gard's ethical reservations would stifle hope for a range of diseases, the ad suggests. These include Alzheimer's, which most scientists acknowledge is probably beyond stem cell cures.
This ad employs clever rhetorical jiujutsu to trip up opponents with the force of their own arguments. Dobson, for instance, is quoted as saying "Lowering that standard is also likely to lead to human cloning and harvesting of body parts conceived for this purpose." But heightening the ethical danger doesn't work; it only makes him look ridiculous, at least to viewers in the Badger State.
Similarly, the Wisconsin race for governor pits incumbent Jim Doyle against Mark Green, who this woman says is "too extreme" for the job because he opposes stem cell research. (Governor Doyle, on the other hand, has just handed over US$1 million to a private company started by the scientist who first isolated human embryonic stem cells, James Thompson.)
And finally, rubber-faced comedian Jon Stewart has a field day with Senator Sam Brownback's defense of embryo rights.
Even though Brownback's supporters would no doubt cheer his folksy explanations, Stewart's ridicule suggest that vast swathes of American voters simply cannot comprehend his point of view.
There is one YouTube video opposing therapeutic cloning. Missourians are voting on an amendment to the state constitution which would bulletproof it from legislative interference.
This ad focuses on "biotech special interests who stand to gain millions of dollars". It takes a more cerebral approach and has little of the emotional punch of the pro-research ads.
Finland: after years of delay the Finnish parliament has approved a law which allows single women and lesbians to receive fertility treatment. The legal affairs committee had endorsed a more restrictive version of the law, which would have limited treatment to a heterosexual couple. ~ Helsingin Sanomat, Oct 17
Killer nurse: A 40-year-old nurse has been sentenced to life in a Texas prison for giving ten of her elderly patients lethal injections. The patients had been hospitalised for minor ailments, such as a foot sore, diarrhoea or dementia. Why Vickie Jackson became a murderer is still a mystery. FBI agent David Burns speculated that the patients were probably demanding and annoying, so she killed them. Ms Jackson pleaded no contest to the charges but still insists that she is innocent. ~ AP, Oct 3
Japanese surrogacy: A woman in her 50s gave birth to her daughter's baby last year, in Japan's first case of mother-daughter surrogacy. The daughter's uterus had been removed because of cancer and she was unable to bear children. ~ BBC, Oct 15
Serono: Serono, a Swiss pharmaceutical company which supplies many of the world's IVF clinics, has been sold to Merck for US$1 billion. ~ rbmonline.com, Oct 16
Prizes: Elizabeth Blackburn, an Australia-American who is an expert in the cellular basis of ageing, has won two prestigious scientific prizes in the past month. The first was the Lasker Prize, often seen as a step towards a Nobel prize, and the second was the Gruber Genetics Prize. The organisers of the latter praised her "fight against the politicisation of science". To the wider public, Dr Blackburn is better known for being dropped from the President's Council on Bioethics. She insisted that she had been fired because she supported embryonic stem cell research.
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