One of Australia's best-known scientists has been appointed head of the California Institute for Regenerative Medicine. Alan Trounson, 61, has been brought in to manage a US$3 billion budget for an organisation dogged by controversy from its inception. He is renowned internationally as an IVF pioneer and a leading figure in embryonic stem cell research.
California is soon to begin issuing $250 million in bonds to finance the institute, which has been surviving on loans and private donations while it battled lawsuits with its disgruntled opponents. In this uncertain environment management of the CIRM has proved difficult and several top executives and scientists have left in recent months. But the CIRM board is confident that Dr Trounson will make up for lost time.
The Australian has a stellar reputation in his field. A director of the CIRM board described him as "a world renowned stem cell researcher, [with] significant management/administrative experience, significant private sector experience, significant translational experience, a clear well-articulated scientific vision, demonstrated leadership experience, experience with the public, media and political leaders (and the) ability to position CIRM to realise its potential as a global engine for stem cell research."
Dr Trounson was a leading figure in a heated 2002 debate in Australia over the potential of embryonic stem cell research and whether it should be legalised. He was criticised for showing parliamentarians a video of a crippled rat which had been "cured" with embryonic stem cells. It turned out that the rat had been treated with embryonic germ cells derived from a five to nine-week-old human foetus. Dr Trounson apologised and said that he had learned "a very valuable lesson about ensuring precision in what you say to people".
Dr Trounson has always been a prominent defender of the right of scientists to conduct research on human embryos. But, curiously for the head of an organisation which was sold to voters as a source of life-saving cures, he has often expressed scepticism about the therapeutic potential of embryonic stem cells. "The so-called therapeutic cloning to my mind is a non-event," he told Nature Medicine in 2005. As a method for developing cures for dread diseases, "it's just not realistic." ~ Nature Medicine, Apr 28, 2005; Los Angeles Times, Sept 15
LESBIAN PAIR SUES OVER ONE IVF CHILD TOO MANY
Now for another quirky moment in the world of artificial reproductive technology, this time from Australia's capital, Canberra. A lesbian couple has launched a wrongful birth suit after the mother gave birth to twin girls instead of the single girl the couple wanted. They are claiming A$400,000 for the cost of raising one of them up to the age of 21.
The fertility clinic admits that the woman mentioned on the day that she wanted only one embryo to be implanted, but points out that she had signed a pre-admission form in which she consented to one or two.
The woman and her partner allege that the twin pregnancy jeopardised their careers, their relationship and their health. They also had to scrap plans for a trip to England. The mother suffered pre- and post-natal depression and could only work a few hours at a time because of the pain. The couple needed relationship counselling for about 18 months.
One solution would have been foetal reduction, but that would have put the other child at risk. Another was adoption, but that would have been too emotionally wrenching for the women.
The sperm for the pregnancy came from a Danish sperm bank because the father of one of the women was German. The women's lawyer has asked for their names to be suppressed as it could be distressing for their daughters to discover that their parents had not wanted them. ~ Canberra Times, Sept 18
HIPPOCRATIC OATH FOR SCIENTISTS PROPOSED
The British government's chief scientific adviser has launched a code of ethics for scientists. Professor Sir David King said that the new code will help to build trust between scientists and the public. It should encourage researchers to reflect upon the impact that their work will have on wider society. The seven principles, a sort of latter-day Hippocratic Oath for scientists, are:
- Act with skill and care, keep skills up to date
- Prevent corrupt practice and declare conflicts of interest
- Respect and acknowledge the work of other scientists
- Ensure that research is justified and lawful
- Minimise impacts on people, animals and the environment
- Discuss issues science raises for society
- Do not mislead; present evidence honestly
~ BBC, Sept 12
IVF ON THE CHEAP -- IF YOU GIVE YOUR EGGS FOR CLONING
Britain's Medical Research Council has agreed to fund half of women's IVF bills, provided that they donate half of their eggs for cloning research. This will bring the cost of IVF down from about 3,000 to £1,500. Professor Alison Murdoch, of the Newcastle Fertility Centre, which will run the pilot program, says that this will ease the financial burden for some infertile women.
Although this development has received all the necessary government approvals, not everyone is happy. The Scottish Council on Human Bioethics called it "scandalous". Its director of research, Dr Calum MacKellar, said that "no rich person would even consider this kind of arrangement". ~ BioNews, Sept 17
VATICAN SUPPORTS FOOD AND WATER
FOR UNCONSCIOUS PATIENTS
It is wrong to stop administering food and water to patients in a vegetative state, even if they never regain consciousness, says the Vatican. A new document approved by Pope Benedict XVI says that tube-feeding such patients is "ordinary care" which should not be discontinued because patients still have human dignity.
An official spokesman, Father Augustine Di Noia, explained that "What we're seeing here is that the quality of life is not a judgment that is in our hands to make. Life is a gift from God, and the Church has consistently taught that it is a gift that is not subject to the determination and decision of anyone, including the person himself or herself who is ill."
Father Di Noia contended that the human person has a "dignity which perdures through all of the various physical states which each person experiences in life from the existence in the womb to the final moments before death. At no point can life be terminated for any reason."
The declaration comes as no surprise, given the Catholic Church's stand in the Terri Schiavo case. But its main purpose is probably to settle disagreements amongst Catholic bioethicists. Some had claimed that previous statements were vague and not authoritative. ~ Reuters, Zenit, Sept 14
EUROPEAN PARLIAMENT BACKS HALT TO APE EXPERIMENTS
A large majority of members of the European Parliament have called for an end to experimentation on great apes. Their resolution is not legally binding, but must be taken into account when legislation is drafted in the European Commission. Animal rights activists claim that more than 10,000 primates are used in experiments in Europe every year. The UK is said to be Europe's largest single user, followed by France and Germany.
Animal rights campaigners were jubilant after their intense lobbying efforts proved victorious. The CEO of Animal Defenders International, Jan Creamer, said: "This Declaration recognises that primates are our closest relatives, with chimpanzees sharing 98% of our DNA - like us, they have forms of language, culture, and live in family groups." And British MEP John Bowis, a health minister in the Major government, commented: "experiments on primates are both unethical and inefficient and can and should be replaced with more advanced scientific techniques". ~ New Scientist, Sept 13; Animal Defenders International, Sept 7
DOUBTS ON CYBRIDS SURFACE
Now that hybrid embryos have effectively been legalised in the UK, doubts about whether they are possible have surfaced in the media. The UK's fertility regulator, the Human Fertilisation and Embryology Authority, recently backed requests by scientists to create so-called "cybrids", formed by fusing human DNA with an enucleated cow or rabbit egg.
However, Dr Robert Lanza, of Advanced Cell Technology, an American company which has been working on hybrid embryos for some time, says that his efforts to do this have been unsuccessful when two species were quite different. "They grow to the 16-cell stage, then just before going on to become blastocysts, they block," he told New Scientist. He suspects that this happens because the animal mitochondria in the cytoplasm stops communicating with the human genetic material.
However, Dr Stephen Minger, who has applied for a licence to use the technique, is planning to send researchers to China to learn how to do it. Researchers at Shanghai Second Medical University claim that they created these hybrids four years ago. He is upbeat about British science. "Just because it hasn't been done, it doesn't mean we shouldn't try it," he told New Scientist. ~ New Scientist, Sept 15
AGGRESSIVE PITCH FOR ORGAN DONATION GIVES SHIVERS IN US
A growing shortage of organs for transplant in the United States has prompted allegations that attempts to get organs from dying patients are too aggressive. The most scandalous case happened last year in San Luis Obispo, California, when an overzealous surgeon may have overstepped the line between waiting until the donor, a disabled 25-year-old man, died, and deliberately hastening his death.
The president of the Association of Organ Procurement Organizations (OPOs), Thomas Mone, insists that this case was an aberration. However, doctors, nurses, and others say that they have noticed a growing pressure to supply organs since 2003, when the Federal government launched a campaign to maximise the supply of organs from deceased donors. The employees of the OPOs work with hospitals to identify potential donors.
Some bioethicists are critical of how the OPOs work. "It's like they're vultures flying around the hospitals hovering over beds waiting for them to die so they can grab the organs," says Michael Grodin, of Boston University.
And bioethicist Daniel O. Dugan told the Washington Post: "In some places, the organ-procurement folks will actually go into the room and meet the family and wear scrubs that are the same colour as the hospital personnel and allow themselves to be experienced by the family as being members of the hospital staff... They will introduce themselves and build a kind of rapport when actually their whole agenda is organ procurement."
Apparently OPO representatives are trained to persuade families to donate the organs of family members by describing dying patients who are desperate for organs. They also adopt a "presumptive" approach which assumes that the family would like to donate. ~ Washington Post, Sept 13
BRITONS CHEERY ABOUT ORGAN DONATION
Britons have a positive attitude towards organ donation, but few translate their good intentions into deeds. In a recent survey conducted for the Human Tissue Authority, 68% of people indicated that they would probably donate organs or tissue. However, only 5% had done anything about it.
The main issue centred on consent. Nearly half said they would be happy for their tissue or organs to be used with their prior consent. About 33% thought it acceptable for their family members to give consent on their behalf after their death, and 19% believed that it was never acceptable to use tissue or organs for any purpose without the consent of the individual or family. About 1 in 6 people had no opinion on the topic. ~ BMJ, Sept 15
How to support BioEdge
BioEdge and ABI's other services rely completely upon the generosity of private benefactors and volunteer workers. ABI has no institutional backing. If you would like to support the best bioethics news service on the Web, you can do it painlessly through Paymate, a thoroughly reliable payment service which is affiliated with the internet auction site eBay.
Just access the Paymate website and follow the instructions. You will need to fill in our email address, which is bioedge@australasianbioethics.org. You will also have to give your credit card details and an amount in Australian or US dollars. Thanks!
|
To subscribe to our weekly email newsletter,
click here for the HTML version.
click here for the text version.
To cancel your newsletter subscription, click here.
Australasian Bioethics Information
ISSN 1446-2117
Website:www.australasianbioethics.org
BioEdge editor: Michael Cook
New Zealand Contributing Editor: Carolyn Moynihan
The BioEdge privacy policy
Your subscription information will be kept private and is not publicly accessible.
Your email address and other information will never be sold to a third party or given out
without your consent. You may cancel your subscription at any time.
|